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Diabetes, insulin and the CDL

By Vadym Starynets, editor and publisher · Checked against the eCFR text as of September 18, 2026 · How we work

Yes, you can get a CDL with diabetes, including diabetes treated with insulin. Diabetes not treated with insulin has no separate federal standard and goes through the ordinary exam. Insulin-treated diabetes goes through 49 CFR 391.46: your treating clinician completes Form MCSA-5870, you see a certified medical examiner within 45 days, and the certificate lasts at most 12 months. The old insulin exemption programme ended when that rule took effect on 19 November 2018.

Two routes

Diabetes not treated with insulinInsulin-treated diabetes
RuleNo specific standard; the general standards in 391.41(b) apply391.41(b)(3) points to 391.46
Extra paperworkNone required by ruleMCSA-5870 from the treating clinician for every exam
Maximum certificate24 months (391.45(b)), or less at the examiner's discretion12 months (391.45(e))
RecordsAs your examiner requestsAt least 3 months of electronic glucometer records for a full 12-month card

The column you are in depends on treatment, not on the type of diabetes. A driver who moves from tablets to insulin moves from the left column to the right one, and the example further down shows what that means in practice.

Diabetes not treated with insulin

Standard 391.41(b)(3) is about insulin only: no established medical history or clinical diagnosis of diabetes currently treated with insulin for control, unless the person meets 391.46. Diabetes managed by diet, tablets or non-insulin injections does not trigger it. When FMCSA wrote the insulin rule in 2018 (83 FR 47486), it considered a recommendation to require annual certification for all drivers with diabetes and rejected it, agreeing that a two-year period for non-insulin drivers is appropriate, while noting examiners may issue shorter certificates for conditions that need monitoring.

The examiner still considers complications under the other standards, for example vision under 391.41(b)(10) and nerve or circulation problems under 391.41(b)(7). The urinalysis on the MCSA-5875 records sugar, and the form notes that sugar in the urine may be a reason for further testing. In its January 2024 Handbook notice (89 FR 3892), FMCSA said it had added considerations for examiners on non-insulin diabetes and was seeking approval for an optional Non-Insulin-Treated Diabetes Mellitus Assessment Form. We could not confirm from an FMCSA source whether that form has since been approved.

Insulin-treated diabetes: the 391.46 process, step by step

  1. Treating clinician evaluation. Before the exam required by 391.45, or before your certificate expires, you must be evaluated by your "treating clinician": the healthcare professional who manages, and prescribes insulin for, your diabetes as authorized by their state licensing authority (391.46(b)). The clinician completes the Insulin-Treated Diabetes Mellitus Assessment Form, MCSA-5870, and signs and dates it with full name, office address and phone number (391.46(b)(1) and (2)).
  2. Examiner visit within 45 days. At least annually, and no later than 45 days after the clinician signs the MCSA-5870, you must be examined and certified by a medical examiner as physically qualified and as free of diabetes complications that might impair safe driving (391.46(c)).
  3. The form goes in the file. The examiner must receive a completed, signed MCSA-5870 for each required exam, and keeps it as part of the MCSA-5875 report (391.46(c)(1)).
  4. The examiner decides. The examiner considers the clinician's form but uses independent medical judgement and applies the standards in 391.46(c)(2), below.

The standards the examiner applies

The glucometer requirement

391.46(d) requires you to self-monitor blood glucose as your treating clinician prescribes, and to keep records measured with an electronic glucometer that stores all readings, records the date and time of each, and allows the data to be electronically downloaded. You must give the clinician a printout of the records or the glucometer itself at each evaluation. The rule describes the device by those functions rather than by type; if you use a continuous glucose monitor, ask your clinician and examiner whether its records meet this description before relying on it.

Severe hypoglycemia after certification

391.46(e) is the one part of the rule that takes effect on the road. A severe hypoglycemic episode is one that requires the assistance of others, or results in loss of consciousness, seizure or coma. If you have one after being certified:

The certificate in your wallet does not override this. Separately, 392.3 bars driving while alertness is impaired or likely to become impaired through illness.

The insulin route as a timeline

WhenWhat happensRule
From the start of insulinSelf-monitor as the clinician prescribes, on an electronic glucometer that stores, time-stamps and downloads readings391.46(d)
Before the exam or certificate expiryTreating clinician evaluates you and signs the MCSA-5870391.46(b)
Within 45 days of that signatureMedical examiner exam and certification391.46(c)
At the examUp to 12 months with at least 3 months of records; no more than 3 months without them391.46(c)(2)(iii), (iv); 391.45(e)
Any time after certificationSevere hypoglycemic episode: stop driving until the clinician's steps are complete391.46(e)
Every yearRepeat the clinician evaluation and the exam391.46(c); 391.45(e)

Who counts as your treating clinician

The rule defines the role by what the person does, not by specialty: a healthcare professional who manages, and prescribes insulin for, your diabetes, as authorized by their state licensing authority (391.46(b)). That can be a family doctor, an endocrinologist, or another professional whose state license allows it, such as a nurse practitioner where state law permits, as long as they manage your diabetes and prescribe your insulin. If two people share your care, the one who manages the diabetes and prescribes the insulin is the one who signs. This was a deliberate change. Under the old exemption programme, as the 2018 rule describes it, an applicant had to be examined by a board-certified or board-eligible endocrinologist. The examiner is a separate person with a separate role: the clinician reports on control and stability, and the examiner decides qualification using independent judgement (391.46(c)(2)).

Complications the examiner looks for

Section 391.46(c) requires the examiner to find you free of complications from diabetes that might impair your ability to drive safely. The permanent retinopathy disqualification in (c)(2)(ii) is the only complication the rule names, but the other standards in 391.41(b) still apply in full. Vision is checked under 391.41(b)(10). Loss of sensation or strength in the feet or hands falls under 391.41(b)(7). FMCSA's 2024 Handbook notice also says it moved the Handbook's discussion of renal dialysis into the diabetes section, because diabetes leads to more kidney disease than cardiovascular disease does. Bring records of any eye examination and of any treatment for complications.

What the rule does not require

The 2018 rulemaking record is useful here, because FMCSA explained what it deliberately left out:

One restriction did stay. FMCSA kept its position that insulin-treated drivers licensed in Canada or Mexico may not drive commercial vehicles in the United States: under the reciprocity agreement with Canada a Canadian insulin-treated driver is not authorized to drive here, and Mexico does not issue its federal commercial license to insulin-treated drivers.

The old exemption programme

Before 19 November 2018, insulin-treated drivers could drive interstate only with an FMCSA exemption. The 2018 rule's summary says it lets a certified examiner grant a certificate of up to 12 months instead, and its cost analysis states that the exemption programme will be eliminated. There is no current "diabetes waiver" to apply for; the route is 391.46.

Example: starting insulin mid-certificate

Illustration of the rule, not medical advice. A driver on tablets with a two-year card starts insulin in March. Two things follow. His existing certificate was issued under the general standard, but once he uses insulin, 391.41(b)(3) is satisfied only by meeting 391.46, so he should speak to his examiner rather than rely on the old card; 391.45(e) also puts insulin-treated drivers on a 12-month maximum. He has no electronic glucose history on insulin yet, so if he is examined in April, 391.46(c)(2)(iv) limits him to a certificate of no more than 3 months. He uses a downloadable glucometer from day one. In July, with 3 months of records, his clinician completes a new MCSA-5870 on 2 July, and he sees the examiner on 10 July, well inside the 45-day window, who can now certify him for up to 12 months.

Common mistakes

Certified examiners are listed by city in the DOT physical directory. How the 12-month interval fits with the other certificate periods is on the certificate validity page, and insulin alongside other medicines is covered on which medications CDL drivers can take.

Questions

Can you get a CDL with diabetes?
Yes. Diabetes not treated with insulin has no separate federal standard and is judged at the ordinary exam. Insulin-treated diabetes is allowed under 49 CFR 391.46, with a treating clinician's MCSA-5870 and a certificate of up to 12 months.
Can CDL drivers take insulin?
Yes, since 19 November 2018. 49 CFR 391.41(b)(3) sends insulin-treated drivers to 391.46, which requires a stable insulin regimen, proper control, an MCSA-5870 from the treating clinician, and an exam within 45 days of the clinician signing it.
What is the MCSA-5870?
The Insulin-Treated Diabetes Mellitus Assessment Form. Your treating clinician, the professional who manages your diabetes and prescribes your insulin, completes, signs and dates it before each exam under 49 CFR 391.46(b). The examiner keeps it with your MCSA-5875.
Is there an A1C limit for a DOT physical?
No. When FMCSA adopted the insulin rule in 2018 it declined to set one, saying HbA1c should not be the sole measure of safety and is one factor the treating clinician may consider (83 FR 47486).
How long is a medical card with insulin-treated diabetes?
At most 12 months under 49 CFR 391.45(e), and no more than 3 months until you have given your clinician at least 3 months of electronic glucose records while on insulin (391.46(c)(2)(iii) and (iv)).
Is there still a CDL diabetes waiver or exemption?
No. The 2018 rule replaced the FMCSA exemption programme with the 391.46 process run by treating clinicians and medical examiners.
What happens after a severe low blood sugar episode?
Under 49 CFR 391.46(e) you may not drive a commercial vehicle until a treating clinician has found the cause addressed, confirmed a stable regimen and proper control, and completed a new MCSA-5870. You keep the form for your next exam.
Can an insulin-treated driver haul hazmat or passengers?
Yes. The federal rule has no restriction by cargo or passenger type; FMCSA concluded in 2018 that drivers with stable, properly controlled insulin-treated diabetes can operate any category of commercial vehicle.
Which conditions permanently disqualify an insulin-treated driver?
Severe non-proliferative or proliferative diabetic retinopathy. 49 CFR 391.46(c)(2)(ii) says a driver with either is not physically qualified on a permanent basis.

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